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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
27.58
Human Site:
S14
Identified Species:
60.67
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
S14
S
Y
S
Y
D
A
P
S
D
F
I
N
F
S
S
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
S14
S
Y
S
Y
D
A
P
S
D
F
I
N
F
S
S
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
S14
S
Y
S
Y
D
A
P
S
D
F
I
N
F
S
S
Dog
Lupus familis
XP_850934
748
86144
T14
S
Y
S
Y
D
A
P
T
D
F
I
N
F
T
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
T14
T
Y
S
F
D
A
P
T
D
F
I
N
F
S
S
Rat
Rattus norvegicus
NP_001101260
744
85432
T14
A
Y
S
F
D
A
P
T
D
F
I
N
F
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
K12
K
T
S
G
H
V
T
K
T
V
D
F
H
F
C
Chicken
Gallus gallus
NP_989768
739
85048
F15
V
P
N
P
C
I
N
F
A
T
L
S
D
D
D
Frog
Xenopus laevis
NP_001086751
715
81991
S14
T
Y
S
Y
D
A
P
S
I
F
N
F
S
S
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
T102
E
H
L
Q
E
T
T
T
N
S
I
Q
D
T
E
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
P33
E
A
Y
E
F
S
A
P
K
F
Y
D
F
V
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
0
60
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
20
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
64
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
64
0
0
0
55
0
10
10
19
10
10
% D
% Glu:
19
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
19
10
0
0
10
0
73
0
19
64
10
10
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
10
0
64
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
10
0
10
55
0
0
0
% N
% Pro:
0
10
0
10
0
0
64
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
37
0
73
0
0
10
0
37
0
10
0
10
10
55
55
% S
% Thr:
19
10
0
0
0
10
19
37
10
10
0
0
0
19
0
% T
% Val:
10
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
64
10
46
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _